::欢迎访问夏安东研究员课题组:: (English)   分子反应动力学国家重点实验室   中科院化学所


夏安东 研究员


办公室：化学所2号楼204室
电话：010-62562865
传真：010-62563167
电子信箱：andong@iccas.ac.cn

生于：1964年

    简历:

  • 1987年 毕业于南京师范大学物理系
  • 1990年 获得中国科学院长春物理所固体物理专业  硕士学位
  • 1993年 获得中科院感光化学所有机化学专业  博士学位
  • 1993年－1995年 中国科技大学国家同步辐射实验室  博士后
  • 1995年－1997年 任同步辐射实验室  副研究员
  • 1997年－1998年 日本理化学研究所光动力研究中心Frontier Research Program  研究员
  • 1998年－1999年 中国科技大学精密机械和精密仪器系  副研究员
  • 1999年－2000年 韩国国家标准科学研究院激光光谱实验室  博士后
  • 2000年－2001年 美国耶鲁大学医学院神经科学系  博士后
  • 2001年6月 应聘进入中国科学院"引进海外杰出人才计划"，成为中国科学院化学研究所分子科学中心  研究员、博士生导师
  • 同期兼任中国科技大学精密机械与精密仪器系  兼职教授
  • 2005年10月－2006年3月 日本东北大学多元物质科学研究所软x光显微镜研究中心  客座教授
  • 2009年 1月－现在 获得国家自然科学基金委杰出青年基金资助

     

  研究领域和兴趣:
（1）超大分子的激发态动力学过程的研究：

利用超快激光光谱技术(fs激光技术，Pump-probe和time-correlated single photon counting )研究超大分子的光异构化动力学特性。主要有:

  • 以azo等为基础的分子体系系列(包括以此为基础的枝状超大分子体系)
  • 无机和有机复合体系的光致变色体系
  • 光色生物蛋白（bR, GFP等）

    单个分子(单个纳米粒子)的激发态动力学特性：利用双光子激光扫描荧光显微镜及其相应的超敏探测手段研究单个分子(单个纳米粒子)的激发态动力学特性。主要有:
  • 单个介孔或微腔中的装填的客体分子或半导体体系与介孔(主体)介质之间的电荷(或电子)转移的超快动力学特性
  • 微晶界面间光诱导的电荷转移及其光生载流子扩散的超快动力学过程?单个生物光色集团(单个光合光系统反应中心)中各色团之间的相互作用

    （2）单分子光谱方法及其应用研究:
  • 单分子光谱方法研究
  • 单个生物大分子（蛋白质、ＤＮＡ等）的折叠动力学过程
  • 光合作用过程中的状态转换过程中的相关捕光色素蛋白及其调控蛋白的结构与功能的单分子水平研究
  • 单个生物光色集团(单个光合光系统反应中心)中各色团之间的相互作用、单个反应中心外周蛋白的结构与功能的研究

    （3）量子化学反应控制、飞秒的荧光上转换、基于飞秒的非线性光学方法的研究


    （4）双光子微加工、三微高密度数据存储的新方法、新机理研究


      研究方法:

  • 白光的飞秒pump-probe技术
  • 飞秒时间分辨光学克尔效应和荧光上转换、荧光亏蚀系统
  • 单光子和双光子激发的时间相关的单光子计数技术
  • 与超快光谱和超敏探测技术相结合的共焦激光扫描荧光显微镜


    　     发表文章:

  • Xia Andong, Zhu Jinchang, Jiang Lijin and Zhang Xinyi., Energy transfer kinetics in C- phycocyanin from cyanobacterium Westiellopsis prolifica studied by pump-probe techniques. Biochem. Biophys. Res. Comm. 179, 558-564(1991).
  • Xia Andong, Zhu Jinchang, Wu Huaju, Jiang Lijin, Sudha M, Maruthi Sai P. S., Time-resolved polarized absorption of C-PC from cyanobacterium Westiellopsis prolifica. J. Photochem. Photobiol. B. Biology, 19, 111-117(1993).
  • Xia Andong Pan Haibin, Zhang Xinyi, Fu Shaojun. Enhancement of fluorescence and Raman spectroscopies of undoped C60 film. J. Lumin. 63(1995)301-308
  • Xia Andong, Fu Shanjun, Zhang Xinyi. Characteristics of heterojunction diode of C60/InPcCl Solid State Comm., 95(1995)713-716.
  • Xia Andong, Fu Shaojun, Hong Yiling, Tian Yangchao, Hu Yiguan, Zhang Xinyi, Ultrafine pattern x-ray mask fabricated using sidewall methods. J. Vac. Sci. Technol. (B), 14(1996)3391-3392.
  • Xia Andong, Wada Satoshi, Tashiro Hideo, Optical data storage in C60 doped polystyrene film by photooxidation. Appl. Phys. Lett. 73(1998)1323-1325.
  • Xia Andong, Wada Satoshi, Tashiro Hideo, Huang Wenhao One- and wo-photon-indunced fluorescence from green fluorescent protein, Arch. Biochem Biophys., 382(1999)280-284.
  • J. Liu , Y.W. Zhao , J.Q. Zhao , A.D. Xia, L.J. Jiang , S. Wu , L. Ma , Y.Q. Dong , Y.H. Gu, Two-photon excitation studies of hypocrellins for photodynamic therapy, J. Photochem. Photbiol. B-Biol. 68 (2002) 156–164.
  • Wada Satoshi, Xia Andong, Tashiro Hedio, 3D optical data storage with two-photon induced photon-oxidation in C60-doped polystyrene film. RIKEN Rev., 2002, 49(11):52-54.
  • Jiang Zhongwei,Zhou Yongjun,Yuan Dajun,Huang Wenhao, Xia Andong.　A two-photon femtosecond laser system for three-dimensional microfabrication and data storage. Chin. Phys. Lett. 2003, 20, 2126-2129.
  • Xuejun Duan, Zhen Zhao, Jianping Ye, Huimin Ma, Andong Xia, Guoqiang Yang, and Chih-Chen Wang, N-Terminal fluorophore labeling combined with donor-donor energy migration for study on unfolding of dimeric DsbC, Angew Chem, 43,4216-4219(2004)
  • Zhi Yang, Zhikun Wu, Jinshi Ma, Andong Xia, Quanshui Li, Chunling Liu, Qihuang Gong. Large optical power limiting from novel self-assembly organic complexes, Appl. Phys. Lett., 86, 061903 (2005)
  • Zhengxi Huang, Dongmei Ji, Andong Xia,　Resonance Photoinduced Reverse Intersystem Crossing from Cy 5 molecules by Single Wavelength Excitation, Colloids and Surfaces A: Physicochem. Eng. Aspects, 257 (2005)203-209
  • Zhi Yang, ZhiKun Wu, J.S.Ma, A.D.Xia, One-and Two-Photon-Induced Fluorescence fromNovel Compounds Formed by Self-Assembly of Pyrrol-2-yl-methyleneamines with Zinc(II), Colloids and Surfaces A: Physicochem. Eng.Aspects, 257-258c (2005)515-519
  • Yongjun Zhou, Huohong Tang, Wenhao Huang, Andong Xia, Three-dimensional optical data storage in photochromic material with two-photon writing and superlow power readout, Opt. Eng. 44(2005)035202
  • Ji Dongmei, Huang Zhengxi, Xia Andong, Detection of Fluorescence from Single Chlorophyll a Molecules absorbed on Glass Surface, Chin. Phys. Lett., 22, 317－320（2005）
  • Zhengxi Huang, Dongmei. Ji, Andong Xia Felix Koberling, Matthias Patting, Rainer Erdmann, Direct Observation of Delayed Fluorescence from a Remarkable Back-Isomerization in Cy5. J. Am. Chem. Soc. 127(2005)8064-8066.
  • Rui Guo, Zhiyuan Li, Zhongwei Jiang, Dajun Yuan,Wenhao Huang and Andong Xia, Log-pile photonic crystal fabricated by two-photon photopolymerization, J. Opt. A: Pure Appl. Opt. 7(2005)396-399.
  • Guiyuan Jiang,Yanlin Song, Yongqiang Wen, Wenfang Yuan, Huimeng Wu, Zhi Yang, Andong Xia, Min Feng, Shixuan Du, Hongjun Gao, Lei Jiang, Daoben Zhu, High Density Data Recording in an Optoelectrical Dual-Responsive Thin Film,ChemPhysChem, 6(2005)1478-1482.
  • Zhengxi Huang, Dongmei. Ji, Wang Sufan, Andong Xia, Felix Koberling, Matthias Patting, Rainer Erdmann, Spectral identification of triplet state and photoisomerization by means of ensemble and single molecule measurements,J. Phys. Chem. A, 110(2006)45-50.Most-Accessed Articles: January-March, 2006
  • Xunmin Guo, Andong Xia, ultrafast excited states relaxation dynamics in solution investigated by stimulated emission from a styryl dye,J. Luminescence, 122(2007)532-535
  • Rui Guo, Shizhou Xiao, Xiaomin Zhai, Jiawen Li, Andong Xia, and Wenhao Huang. Micro lens fabrication by means of femtosecond two photon photopolymerization,Optics Express,2006,14(2),810-816.
  • Wei Lv, Na Li, Yuliang Li, Ye Li, Andong Xia, Shape Specific detection based on fluorescence resonance energy transfer using a flexible water-soluble conjugated polymer,J. Am. Chem. Soc., 128, 10281-10287,2006.
  • Dongmei Ji, Wei Lv, Zhengxi Huang, Andong Xia, Min Xu, Weimin Ma, Hualing Mi, Teruo Ogawa, Fluorescence resonance energy transfer imaging of CFP/YFP labeled NDH in cyanobacterium cell, J. Luminescence,122(2007)463-466.
  • Ke Jia, Yan Wan, Andong Xia, Shayu Li, Fangbin Gong, Guoqiang Yang, Characterization of Photoinduced Isomerization and Intersystem Crossing of the Cyanine Dye Cy3, J. Phys. Chem. A, 2007,111(2007)1593-1597.
  • Xunmin Guo, Sufan Wang, Andong Xia, Hongmei Su, Determination of the formation of dark state via depleted spontaneous emission in a complex solvated molecule, J. Phys. Chem. A, 2007, 111, 5800-5805.
  • Ying Gong, Xunmin Guo, Sufan Wang, Hongmei Su, Andong Xia, Qingguo He, Fenglian Bai, Photophysical properties of photoactive molecules with conjugated push-pull Structures, , J. Phys. Chem. A, 2007, 111, 5806-5812.
  • Na Li, Ke Jia, Sufan Wang, Andong Xia,Theoretical Study of Spectroscopic Properties of Dimethoxy-p-Phenylene-Ethynylene Oligomers: Planarization of the Conjugated Backbone ,J. Phys. Chem. A. 2007, 111, 9393-9398
  • Xunmin Guo, Yan Wan, Andong Xia, Sufan Wang, Jianyong Liu, and Keli Han. Rapid internal conversion in a symmetric molecule LD 700 studied by means of femtosecond fluorescence depletion. Chinese Physics B 18(2009)142–147.
  • Damir Aulimer, Sufan Wang, Xudong Chen, Andong Xia. Excited State Localization and Delocalization of Internal Charge Transfer in Branched Push-Pull Chromophores Studied by Single Molecule Spectroscopy. J. Am. Chem. Soc. 131(2009)5742-5742.
  • Yan Wan, Qianjin Guo, Xuefei Wang,Andong Xia.Photophysical properties of rhodamine isomers: a two-photon excited fluorescent sensor for trivalent chromium cation (Cr+3). Anal. Chim. Acta, 665 (2010) 215–220.
  • Mingli Jia, Xiaonan Ma, Linyin Yan, Haifeng Wang, Qianjin Guo, Xuefei Wang, Yingying Wang, Xiaowei Zhan, Andong Xia. Photophysical properties of intramolecular charge transfer in two newly synthesized tribranched donor-pi-acceptor chromophores. J. Phys. Chem. A. 114(2010)7345-7352.
  • Huan Wang,Hongmei Su, Hualei Qian, Zhaohui Wang, Xuefei Wang and Andong Xia. Structure-dependent all-optical switching in graphene nanoribbon-like molecules: fully conjugated tri(perylene bisimides). J. Phys. Chem. A, 114(2010) 9130-9135.
  • Yan Wan, Linyin Yan, Zujin Zhao,Xiaonan Ma, Qianjin Guo, Mingli Jia, Ping Lu, Gabriel Ramos-Ortiz, José Luis Maldonado, Mario Rodríguez, Andong Xia. Gigantic two-photon absorption cross sections and strong two-photon excited fluorescence in pyrene core dendrimers with fluorene/carbazole as dendrons, and acetylene as linkages. J. Phys. Chem. B, 114(2010) 11737-11745.
  • Xiaonan Ma, Linyin Yan, Xuefei Wang, Qianjin Guo and Andong Xia.Determination of the Hydrogen-Bonding Induced Local Viscosity Enhancement in Room Temperature Ionic Liquids via Femtosecond Time-Resolved Depleted Spontaneous Emission. J. Phys. Chem. A, 115 (27)(2011)7937–7947.
  • Xiaonan Ma, Linyin Yan, Xuefei Wang, Qianjin Guo, and Andong Xia, Spectral and Intramolecular Charge Transfer Properties in Terminal Donor/Acceptor-Substituted all-trans-alpha,omega-Diphenylpolyenes and alpha,omega-Diphenyyynlpoles, PhysChemChemPhys,2011, accepted.
  • Linyin Yan, Xudong Chen, Qingguo He, Yingying Wang, Xuefei Wang, Qianjin Guo, Fenglian Bai, and Andong Xia , Damir Aumiler and Silvije Vdovic , ShengHien Lin, Localized Emitting State and Energy Transfer Properties of Quadrupolar Chromophores and (Multi)Branched Derivatives, J. Phys. Chem. A,2012, 116 , 8693–8705.
  • Boxuan Li, Yingying Wang, Xuefei Wang, Silvije Vdovic, Qianjin Guo,Andong Xia, Spectroscopic Evidence for Unusual Microviscosity in Imidazolium Ionic Liquid and Tetraethylene Glycol Dimethyl Ether Cosolvent Mixtures, yynlpoles, J. Phys. Chem. B, 116(2012)13272-13281.
  • Boxuan Li, Meng Qiu, Saran Long, Xuefei Wang, Qianjin Guo, and Andong Xia, Unraveling Heterogeneous Microviscosities in the Ionic Liquids 1-Alkyl-3-Methylimidazolium Hexafluorophosphate with Different Chain Lengths, PhysChemChemPhys, 2013, 15, 16074-16081
  • Meng Zhou, Silvije Vdovi?, Saran Long; Man-Zhou Zhu, Linyin Yan, Yingying Wang, Yingli Niu, Xuefei Wang, Qianjin Guo, Rongchao Jin, and Andong Xia, Intramolecular Charge Transfer and Solvation Dynamics of Thiolate-Protected Au20(SR)16 Clusters Studied by Ultrafast Measurement, J. Phys. Chem. A, 2013, 117, 10294–10303
  • Meng Qiu, Saran Long, Boxuan Li, Linyin Yan, Weiwei Xie, Yingli Niu, Xuefei Wang, Qianjin Guo, and Andong Xia, Toward an Understanding of How the Optical Property of Water Soluble Cationic Polythiophene Derivative Altered by Addition of Salts: The Hofmeister Effect, J. Phys. Chem. C, 2013, 117, 21870–21878
  • Silvije Vdovic, Yingying Wang, Boxuan Li, Meng Qiu, Xuefei Wang, Qianjin Guo, and Andong Xia, Excited State Dynamics of β-Carotene Studied by Means of Transient Absorption Spectroscopy and Multivariate Curve Resolution Alternating Least-Squares Analysis, PhysChemChemPhys, 2013, 15, 20026-20036

    •   学术会议:

    [1] Andong Xia, Determination of the Dark Processes via Depleted Spontaneous Emission in Complex Solvated Molecules. The 6th Asia Pacific Laser Symposium, Jan 29-Feb 1, 2008, Nagoya, Japan. (invited talk)
    [2] Andong Xia, Specific spectral properties and shape-specific conformation detection during FRET measurements, the 6th International conference on photonics and imaging in biology and medicine, Nov 4-6, 2007, Wuhan, P.R.China. (invited talk)
    [3] Andong Xia, (Hot Topic)， Specific Spectral Phenomena Observed During FRET Measurements, 第十界全国化学动力学会议，2007年9月21日-24日，辽宁大连. 中国
    [4] Andong Xia，Specific spectral properties observed during FRET measurements, the 2nd Annual Advanced Optical Methods Workshop, May 29-31, 2007, Shenzhen, P. R. China. (invited talk)
    [5] Andong Xia, Observation of Unexpected Spectral Phenomena During FRET Measurements, 1st Asian Conference for Spectroscopy and 1st Asian Conference for Biospectroscopy, Jan 29-Feb 3, 2007, Bangalore, India. (invited talk)
    [6] Andong Xia, Shape Specific Detection Based on FRET Using a Flexible Water-soluble Conjugated Polymer, 12th International Workshop on “Single Molecule Spectroscopy and Ultrasensitive Analysis in Life Sciences”, Sept 20-22, 2006， Berlin, Germany. (invited talk)
    [7] Andong Xia, (Oral) Spectral Identification of Triplet State and Photoisomerization by Means of Ensemble and Single-Molecule Measurements, 12th international conference on unconventional photoactive systems, October 2-6, 2005, Sendai，Japan.
    [8] Andong Xia，Identification of Triplet State and Photoisomerization by Means of Ensemble and Single-Molecule Measurements,　全国分子反应动力学学术会议，2005年9月, 杭州. (invited talk)
    [9] Andong Xia, (Oral) Identification of Triplet State and Photoisomerization by Means of Ensemble and Single-Molecule Measurements, The 14th International Conference on Luminescence ICL' 05，Jul 2005, Beijing.
    [10] Andong Xia, (Oral) N-Terminal Fluorophore Labeling Combined with Donor-Donor Energy Migration for Study on Unfolding of Dimeric DsbC, 10th International Workshop on "Single Molecule Detection and Ultra Sensitive Analysis in the Life Sciences", September 22-24 2004, Berlin，German.

    仪器工作室:

    实验室开发新的仪器和方法，同时竭诚为国内大学或研究所的课题组定做和研发下列的技术和仪器：

    • 飞秒时间分辨pump－probe技术 （UV-Vis-NIR 白光探测技术、荧光上转换光谱技术）
    • 飞秒时间分辨荧光亏蚀谱仪和飞秒时间分辨Kerr技术
    • 时间分辨单分子荧光显微镜（FRET、 FCS和单分子荧光光谱等）
    • 飞秒时间分辨CARS谱仪 和 飞秒受激Raman光谱仪

    小组成员:

    在职职工

    郭前进 (2009- ) 副研究员

    访问学者
    牛英利（2012-)

    在读博士生
    龙飒然 (2009- )
    周 蒙 （2010-）
    李 阳 （2012 - ）
    朱华宁 （2012- ）
    何桂营 （2012- ）
    胡江浦 （2013- ）

    已毕业学生
    黄正喜 (Ph. D 2002-2005)
    杨 智 (Ph.D 2000-2005)
    季冬梅 (Ph.D 2001-2006)
    龚 莹 (Ph.D 2002-2007)
    郭逊敏（Ph.D 2002-2007)
    贾 可 (Ph.D 2005-2008)
    丽 娜 (Ph.D 2005-2008)
    吕 维 (Ph.D 2003-2008)
    宛 岩 (Ph.D 2004-2010)
    贾明理 (Ph.D 2007- 2010)
    马晓楠 (Ph.D 2008-2011)
    阎林胤 (Ph.D 2009- 2013)
    李博轩 (Ph.D 2010- 2013)
    王营营 (Ph.D 2008- 2013)
    仇 萌（Ph.D 2012- 2013 )


    访问学者或访问学生
    王素凡 教授 (2006 -2008 安徽师范大学)
    陈旭东 博士 （2007-2008，北京大学)
    Dr. Aumiler Damir (2007.10-2009.6 Institute of Physics Croatia 中科院海外青年科学家)
    Mr. Ly Sonny ( 2008.6-2008.8 University of California Davis)
    Dr. Silvije Vdovic （2011- 2012 )，中科院海外青年科学家

       招聘信息: 研究组拟招聘博士后或者副研究员一名

        本招聘发布时间：2014年3月10日

    • 本招聘长期有效
    • 要求有下面的部分相关知识背景：
    • (a)荧光光谱 和 电化学
      (b)单分子光谱（共聚焦显微镜）
      (c)飞秒光谱技术及其应用
    • 欢迎感兴趣的同学报考本研究组的研究生。
    • 联系人：夏安东
      Email:andong@iccas.ac.cn
      Tel:+86-10-62562865